Name | tenofovir |
Synonyms | PMPA (R)-PMPA TENOFOVIR tenofovir D,L-TENOFOVIR Tenofovir(ForResearchOnly) (R)-9-(2-Phosphonomethoxypropyl)Adenine (R)-9-(2-PHOSPHONYLMETHOXYPROPYL)-ADENINE (R)-9-[2-(phosphonomethoxy)propyl]adenine (R)-9-[2-(Phosphonomethoxy)propyl]adenine(PMPA) 1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid (R)-(1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methylphosphonic acid [[(1R)-2(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic Acid |
CAS | 147127-20-6 |
EINECS | 604-571-2 |
InChI | InChI=1/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1 |
Molecular Formula | C9H14N5O4P |
Molar Mass | 287.21 |
Density | 1.79±0.1 g/cm3(Predicted) |
Melting Point | 276-280°C |
Boling Point | 616.1±65.0 °C(Predicted) |
Specific Rotation(α) | D +21° (c = 1 in 0.1M HCl) |
Water Solubility | 13.4 mg/mL (25 ºC) |
Solubility | H2O: 2 mg/mL |
Appearance | white to beige powder |
Color | white to beige |
Merck | 14,9146 |
pKa | 2.36±0.10(Predicted) |
Storage Condition | -20°C |
MDL | MFCD00943794 |
Physical and Chemical Properties | Melting point 276-280°C water-soluble 13.4 mg/mL (25°C) |
RTECS | SZ6563600 |
HS Code | 29339900 |
Reference Show more | 1. Gong Hongfei, Gao Sheng, Wei Jingchen. Study on the Anti-hepatitis B Virus Effect of Ramie Chlorogenic Acid in Vitro [J]. Journal of Guangxi Academy of Sciences, 2019, 35(01):82-86. 2. Gong Hongfei Pang Fuhua Ruiying et al. Anti-hepatitis B Virus Effect of Three Anti-HBV Nucleoside (Acid) Similar Objects [J]. Experimental Technology and Management 2019 036(009):45-48 56. |
white solid. Melting point 279 °c. Water soluble 13.4mg/mL(25 degrees C). [a]D 210 (c -10.1M HCL). Tenofovir dipentanoyloxymethyl fumarate (Tenofovir diisoproxil Fumar-ate):C19 H30 Ns Oio P.C4 H4 04, white fine crystals.
nucleotide analogs reverse transcriptase inhibitors, which block HIV replication. In combination with other antiretroviral Virus drugs to treat HIV-1 of infections. For the treatment of AIDS.